Biomni is a general-purpose biomedical AI agent designed to autonomously execute a wide range of research tasks across diverse biomedical subfields. By integrating cutting-edge large language model (LLM) reasoning with retrieval-augmented planning and code-based execution, Biomni helps scientists dramatically enhance research productivity and generate testable hypotheses.

Graphiti is a framework for building and querying temporally-aware knowledge graphs, tailored for AI agents in dynamic environments. It continuously integrates user interactions, structured and unstructured data, and external information into a coherent, queryable graph. The framework supports incremental data updates, efficient retrieval, and precise historical queries without complete graph recomputation, making it suitable for developing interactive, context-aware AI applications.

Deep Research is a lightning-fast tool that uses powerful AI models to generate comprehensive research reports in just a few minutes. It leverages advanced 'Thinking' and 'Task' models, combined with an internet connection, to provide fast and insightful analysis on various topics. The tool ensures privacy by processing and storing all data locally. It supports multi-platform deployment, offers support for various large language models, web search functionality, knowledge graph generation, research history preservation, local and server API support, PWA technology, multi-key payload support, multi-language support, and is built with modern technologies like Next.js and Shadcn UI. Deep Research is open-source under the MIT License.

Exosphere is an open source infrastructure designed to run AI agents at scale for large data and long running flows. It allows developers to define plug and playable nodes that can be run on a reliable backbone in the form of a workflow, with features like dynamic state creation at runtime, infinite parallel agents, persistent state management, and failure handling. This enables the deployment of production agents that can scale beautifully to build robust autonomous AI workflows.

BentoML is an open-source model serving library for building performant and scalable AI applications with Python. It comes with everything you need for serving optimization, model packaging, and production deployment.

MetaGPT is a multi-agent framework that enables GPT to work in a software company, collaborating to tackle more complex tasks. It assigns different roles to GPTs to form a collaborative entity for complex tasks. MetaGPT takes a one-line requirement as input and outputs user stories, competitive analysis, requirements, data structures, APIs, documents, etc. Internally, MetaGPT includes product managers, architects, project managers, and engineers. It provides the entire process of a software company along with carefully orchestrated SOPs. MetaGPT's core philosophy is "Code = SOP(Team)", materializing SOP and applying it to teams composed of LLMs.

Fraim is an AI-powered toolkit designed for security engineers to enhance their workflows by leveraging AI capabilities. It offers solutions to find, detect, fix, and flag vulnerabilities throughout the development lifecycle. The toolkit includes features like Risk Flagger for identifying risks in code changes, Code Security Analysis for context-aware vulnerability detection, and Infrastructure as Code Analysis for spotting misconfigurations in cloud environments. Fraim can be run as a CLI tool or integrated into Github Actions, making it a versatile solution for security teams and organizations looking to enhance their security practices with AI technology.

UFO is a UI-focused dual-agent framework to fulfill user requests on Windows OS by seamlessly navigating and operating within individual or spanning multiple applications.

PyLLMCore is a light-weighted interface with Large Language Models with native support for llama.cpp, OpenAI API, and Azure deployments. It offers a Pythonic API that is simple to use, with structures provided by the standard library dataclasses module. The high-level API includes the assistants module for easy swapping between models. PyLLMCore supports various models including those compatible with llama.cpp, OpenAI, and Azure APIs. It covers use cases such as parsing, summarizing, question answering, hallucinations reduction, context size management, and tokenizing. The tool allows users to interact with language models for tasks like parsing text, summarizing content, answering questions, reducing hallucinations, managing context size, and tokenizing text.

Browser Use is a tool designed to make websites accessible for AI agents. It provides an easy way to connect AI agents with the browser, enabling users to perform tasks such as extracting vision and HTML elements, managing multiple tabs, and executing custom actions. The tool supports various language models and allows users to parallelize multiple agents for efficient processing. With features like self-correction and the ability to register custom actions, Browser Use offers a versatile solution for interacting with web content using AI technology.

PremSQL is an open-source library designed to help developers create secure, fully local Text-to-SQL solutions using small language models. It provides essential tools for building and deploying end-to-end Text-to-SQL pipelines with customizable components, ideal for secure, autonomous AI-powered data analysis. The library offers features like Local-First approach, Customizable Datasets, Robust Executors and Evaluators, Advanced Generators, Error Handling and Self-Correction, Fine-Tuning Support, and End-to-End Pipelines. Users can fine-tune models, generate SQL queries from natural language inputs, handle errors, and evaluate model performance against predefined metrics. PremSQL is extendible for customization and private data usage.

OpenMusic is a repository providing an implementation of QA-MDT, a Quality-Aware Masked Diffusion Transformer for music generation. The code integrates state-of-the-art models and offers training strategies for music generation. The repository includes implementations of AudioLDM, PixArt-alpha, MDT, AudioMAE, and Open-Sora. Users can train or fine-tune the model using different strategies and datasets. The model is well-pretrained and can be used for music generation tasks. The repository also includes instructions for preparing datasets, training the model, and performing inference. Contact information is provided for any questions or suggestions regarding the project.

The llama-cpp-agent framework is a tool designed for easy interaction with Large Language Models (LLMs). Allowing users to chat with LLM models, execute structured function calls and get structured output (objects). It provides a simple yet robust interface and supports llama-cpp-python and OpenAI endpoints with GBNF grammar support (like the llama-cpp-python server) and the llama.cpp backend server. It works by generating a formal GGML-BNF grammar of the user defined structures and functions, which is then used by llama.cpp to generate text valid to that grammar. In contrast to most GBNF grammar generators it also supports nested objects, dictionaries, enums and lists of them.

OpenAdapt is an open-source software adapter between Large Multimodal Models (LMMs) and traditional desktop and web Graphical User Interfaces (GUIs). It aims to automate repetitive GUI workflows by leveraging the power of LMMs. OpenAdapt records user input and screenshots, converts them into tokenized format, and generates synthetic input via transformer model completions. It also analyzes recordings to generate task trees and replay synthetic input to complete tasks. OpenAdapt is model agnostic and generates prompts automatically by learning from human demonstration, ensuring that agents are grounded in existing processes and mitigating hallucinations. It works with all types of desktop GUIs, including virtualized and web, and is open source under the MIT license.

The `sec-parser` project simplifies extracting meaningful information from SEC EDGAR HTML documents by organizing them into semantic elements and a tree structure. It helps in parsing SEC filings for financial and regulatory analysis, analytics and data science, AI and machine learning, causal AI, and large language models. The tool is especially beneficial for AI, ML, and LLM applications by streamlining data pre-processing and feature extraction.

Arbigent (Arbiter-Agent) is an AI agent testing framework designed to make AI agent testing practical for modern applications. It addresses challenges faced by traditional UI testing frameworks and AI agents by breaking down complex tasks into smaller, dependent scenarios. The framework is customizable for various AI providers, operating systems, and form factors, empowering users with extensive customization capabilities. Arbigent offers an intuitive UI for scenario creation and a powerful code interface for seamless test execution. It supports multiple form factors, optimizes UI for AI interaction, and is cost-effective by utilizing models like GPT-4o mini. With a flexible code interface and open-source nature, Arbigent aims to revolutionize AI agent testing in modern applications.

Biomni is a general-purpose biomedical AI agent designed to autonomously execute a wide range of research tasks across diverse biomedical subfields. By integrating cutting-edge large language model (LLM) reasoning with retrieval-augmented planning and code-based execution, Biomni helps scientists dramatically enhance research productivity and generate testable hypotheses.

ADMET-AI is a platform for ADMET prediction using Chemprop-RDKit models trained on ADMET datasets from the Therapeutics Data Commons. It offers command line, Python API, and web server interfaces for making ADMET predictions on new molecules. The platform can be easily installed using pip and supports GPU acceleration. It also provides options for processing TDC data, plotting results, and hosting a web server. ADMET-AI is a machine learning platform for evaluating large-scale chemical libraries.

AlphaFold3 is an implementation of the Alpha Fold 3 model in PyTorch for accurate structure prediction of biomolecular interactions. It includes modules for genetic diffusion and full model examples for forward pass computations. The tool allows users to generate random pair and single representations, operate on atomic coordinates, and perform structure predictions based on input tensors. The implementation also provides functionalities for training and evaluating the model.

Generative AI models have shown tremendous usefulness in increasing accessibility and automation of a wide range of tasks. This repository contains the `biochatter` Python package, a generic backend library for the connection of biomedical applications to conversational AI. It aims to provide a common framework for deploying, testing, and evaluating diverse models and auxiliary technologies in the biomedical domain. BioChatter is part of the BioCypher ecosystem, connecting natively to BioCypher knowledge graphs.

ADMET-AI is a platform for ADMET prediction using Chemprop-RDKit models trained on ADMET datasets from the Therapeutics Data Commons. It offers command line, Python API, and web server interfaces for making ADMET predictions on new molecules. The platform can be easily installed using pip and supports GPU acceleration. It also provides options for processing TDC data, plotting results, and hosting a web server. ADMET-AI is a machine learning platform for evaluating large-scale chemical libraries.

AI-Drug-Discovery-Design is a repository focused on Artificial Intelligence-assisted Drug Discovery and Design. It explores the use of AI technology to accelerate and optimize the drug development process. The advantages of AI in drug design include speeding up research cycles, improving accuracy through data-driven models, reducing costs by minimizing experimental redundancies, and enabling personalized drug design for specific patients or disease characteristics.

NVIDIA BioNeMo Framework is a collection of programming tools, libraries, and models for computational drug discovery. It accelerates building and adapting biomolecular AI models by providing domain-specific, optimized models and tooling for GPU-based computational resources. The framework offers comprehensive documentation and support for both community and enterprise users.

New AI Drug Discovery is a repository focused on the applications of Large Language Models (LLM) in drug discovery. It provides resources, tools, and examples for leveraging LLM technology in the pharmaceutical industry. The repository aims to showcase the potential of using AI-driven approaches to accelerate the drug discovery process, improve target identification, and optimize molecular design. By exploring the intersection of artificial intelligence and drug development, this repository offers insights into the latest advancements in computational biology and cheminformatics.

GROMACS Copilot is an agent designed to automate molecular dynamics simulations for proteins in water using GROMACS. It handles system setup, simulation execution, and result analysis automatically, providing outputs such as RMSD, RMSF, Rg, and H-bonds. Users can interact with the agent through prompts and API keys from DeepSeek and OpenAI. The tool aims to simplify the process of running MD simulations, allowing users to focus on other tasks while it handles the technical aspects of the simulations.

Biomni is a general-purpose biomedical AI agent designed to autonomously execute a wide range of research tasks across diverse biomedical subfields. By integrating cutting-edge large language model (LLM) reasoning with retrieval-augmented planning and code-based execution, Biomni helps scientists dramatically enhance research productivity and generate testable hypotheses.