Best AI tools for< Biomedical Research >

Genie TechBio is the world's first AI bioinformatician, offering an LLM-powered omics analysis software that operates entirely in natural language, eliminating the need for coding. Researchers can effortlessly analyze extensive datasets by engaging in a conversation with Genie, receiving recommendations for analysis pipelines, and obtaining results. The tool aims to accelerate biomedical research and empower scientists with newfound data analysis capabilities.

Bionl is a no-code bioinformatics platform designed to streamline biomedical research for researchers and scientists. It offers a full workspace with features such as bioinformatics pipelines customization, GenAI for data analysis, AI-powered literature search, PDF analysis, and access to public datasets. Bionl aims to automate cloud, file system, data, and workflow management for efficient and precise analyses. The platform caters to Pharma and Biotech companies, academic researchers, and bioinformatics CROs, providing powerful tools for genetic analysis and speeding up research processes.

neurons.bio is an AI application that offers a unique collection of over 100 AI agents designed for drug development, medicine, and life science research. These agents perform specific tasks efficiently, retrieve data from various sources, and provide insights to accelerate research processes. The platform aims to revolutionize drug discovery and development by integrating cutting-edge LLM technology with domain-specific agents, reducing research costs and time to clinic.

JADBio is an automated machine learning (AutoML) platform designed to accelerate biomarker discovery and drug development processes. It offers a no-code solution that automates the discovery of biomarkers and interprets their role based on research needs. JADBio can parse multi-omics data, including genomics, transcriptome, metagenome, proteome, metabolome, phenotype/clinical data, and images, enabling users to efficiently discover valuable insights. The platform is purpose-built for various conditions such as cancer, immune, endocrine, metabolic system, chronic diseases, aging, infectious diseases, and mental health, offering solutions for early biomarker discovery, drug repurposing, lead identification, compound optimization, trial monitoring, and response to treatment. JADBio is trusted by partners in precision health & medicine and is continuously evolving to disrupt drug discovery times and costs at all stages.

Genesis Therapeutics is a cutting-edge platform that leverages molecular AI technology to discover and develop highly potent and selective medicines. Their proprietary Generative AI for Drug Discovery (GEMS) platform combines AI and physics research to identify drug candidates against challenging targets with unprecedented speed and accuracy. The company's innovative approach, powered by collaborative minds across AI and biotech, is revolutionizing the drug discovery process.

Ignota Labs is a technology company focused on rescuing failing drugs and bringing new life to abandoned projects, ultimately providing hope to patients. The company utilizes a proprietary AI model, SAFEPATH, which applies deep learning to bioinformatics and cheminformatics datasets to solve drug safety issues. Ignota Labs aims to identify promising drug targets, address safety problems in clinical trials, and accelerate the delivery of therapeutically effective drugs to patients.

Insight is an AI-powered medical research tool that serves as a research assistant for generating scientific summaries, hypotheses, experimental designs, and target identification. It empowers scientists to navigate literature, formulate hypotheses, and design experiments by utilizing peer-reviewed databases to provide reliable outputs. With integrated features like NIH PubMed access, NIH Reporter insights, and MYGENE & MYVARIANT deep dives, Insight streamlines the research process and accelerates discoveries in the medical field.

Boff.ai is an AI tool that connects professionals with academia to unlock opportunities and funding for research and development teams. It helps users ask specific questions across various topics and sources replies from experts in the field. The platform ensures privacy and focuses on solutions required, making it a trusted resource for 30,000 academics and R&D professionals.

The National Cancer Institute's Center for Biomedical Informatics and Information Technology (CBIIT) provides a comprehensive suite of tools, resources, and training to support cancer data science research. These resources include data repositories, analytical tools, data standards, and training materials. CBIIT also develops and maintains the NCI Thesaurus, a comprehensive vocabulary of cancer-related terms, and the Cancer Data Standards Registry and Repository (caDSR), a repository of cancer data standards. CBIIT's mission is to accelerate the pace of cancer research by providing researchers with the tools and resources they need to access, analyze, and share cancer data.

Exscientia is a technology-driven drug design and development company that combines precision design with integrated experimentation to create more effective medicines for patients faster. They operate at the interfaces of human ingenuity, artificial intelligence (AI), automation, and physical engineering, pioneering the use of AI in drug discovery. Exscientia aims to change the underlying economics of drug discovery by rapidly advancing the best scientific ideas into medicines for patients.

Kuano is an AI tool that focuses on redefining drug discovery using Quantum and AI technologies. The platform offers world-class scientific expertise in quantum physics, AI, and medicinal chemistry to revolutionize the drug design process. Kuano aims to leverage cutting-edge technologies to accelerate the discovery of new drugs and improve healthcare outcomes.

SOMA is a Research Automation Platform that accelerates medical innovation by providing up to 100x speedup through process automation. The platform analyzes medical research articles, extracts important concepts, and identifies causal and associative relationships between them. It organizes this information into a specialized database forming a knowledge graph. Researchers can retrieve causal chains, access specific research articles, and perform tasks like concept analysis, drug repurposing, and target discovery. SOMA enhances literature review efficiency by finding relevant articles based on causal chains and keywords specified by the user. It empowers researchers to focus on their research by saving up to 95% of the time spent on pre-processing documents. The platform offers freemium access with extended functionality for 14 days and advanced features available through subscription.

IXICO is a precision analytics company specializing in intelligent insights in neuroscience. They offer a range of services for drug development analytics, imaging operations, and post-marketing consultancy. With a focus on technology and innovation, IXICO provides expertise in imaging biomarkers, radiological reads, volumetric MRI, PET & SPECT, and advanced MRI. Their TrialTracker platform and Assessa tool utilize innovation and AI for disease modeling and analysis. IXICO supports biopharmaceutical companies in CNS clinical research with cutting-edge neuroimaging techniques and AI technology.

HUAWEI Cloud Pangu is an AI tool designed for accelerating drug discovery by optimizing drug molecules. It offers features such as Molecule Search, Molecule Optimizer, and Pocket Molecule Design. Users can submit molecules for optimization and view historical optimization results. The tool is based on the MindSpore framework and has been visited over 300,000 times since August 23, 2021.

Neuralink is a pioneering brain-computer interface (BCI) application that aims to redefine human capabilities by creating a generalized brain interface to restore autonomy to individuals with unmet medical needs. The application focuses on developing fully implantable BCIs that allow users, particularly those with quadriplegia, to control computers and mobile devices using their thoughts. Neuralink's innovative technology includes advanced chips, biocompatible enclosures, and surgical robots for precise implantation. The application prioritizes safety, accessibility, and reliability in its engineering process, with future goals of restoring vision, motor function, and speech capabilities.

Modality.AI is an AI application that has developed an automated, clinically validated system to assess neurological and psychiatric states both in clinic and remotely. The platform utilizes conversational AI to monitor conditions accurately and consistently, allowing researchers and clinicians to review data in near real-time and monitor treatment response over time. Modality.AI collaborates with world-class AI/Machine Learning experts and leading institutions to provide a HIPAA-compliant system for assessing various indications such as ALS, Parkinson's, depression, autism, Huntington's Disease, schizophrenia, and mild cognitive impairment. The platform enables convenient monitoring at home through streaming and analysis of speech and facial responses, without the need for special software or apps. Modality.AI is accessible on various devices with a browser, webcam, and microphone, offering a new approach to efficient and cost-effective clinical trials.

Ascenscia is a specialized AI voice assistant designed to streamline lab digitization processes. It integrates with laboratory software and machines to enable hands-free interactions, automating data collection, optimizing workflows, and accelerating R&D cycles. Ascenscia offers features such as data accessibility, data capturing, inventory access, and additional task management. The application is designed for scientific labs, addressing concerns with precision, safety, and adaptability. It boasts high accuracy in understanding scientific terminologies, end-to-end data encryption, multi-lingual support, and customization options for different lab workflows.

Nucleai is an AI-driven spatial biomarker analysis tool that leverages military intelligence-grade geospatial AI methods to analyze complex cellular interactions in a patient's biopsy. The platform offers a first-of-its-kind multimodal solution by ingesting images from various modalities and delivering actionable insights to optimize biomarker scoring, predict response to therapy, and revolutionize disease diagnosis and treatment.

CEBRA is a machine-learning method that compresses time series data to reveal hidden structures in the variability of the data. It excels in analyzing behavioral and neural data simultaneously, allowing for the decoding of activity from the visual cortex of the mouse brain to reconstruct viewed videos. CEBRA is a novel encoding method that leverages both behavioral and neural data to produce consistent and high-performance latent spaces, enabling the mapping of space, uncovering complex kinematic features, and providing rapid, high-accuracy decoding of natural movies from the visual cortex.

Mind-Video is an AI tool that focuses on high-quality video reconstruction from brain activity data obtained through fMRI scans. The tool aims to bridge the gap between image and video brain decoding by leveraging masked brain modeling, multimodal contrastive learning, spatiotemporal attention, and co-training with an augmented Stable Diffusion model. It is designed to enhance the generation consistency and accuracy of reconstructing continuous visual experiences from brain activities, ultimately contributing to a deeper understanding of human cognitive processes.

This repository serves as a practical guide for Medical Large Language Models (Medical LLMs) and provides resources, surveys, and tools for building, fine-tuning, and utilizing LLMs in the medical domain. It covers a wide range of topics including pre-training, fine-tuning, downstream biomedical tasks, clinical applications, challenges, future directions, and more. The repository aims to provide insights into the opportunities and challenges of LLMs in medicine and serve as a practical resource for constructing effective medical LLMs.

Taiyi (太一) is a bilingual large language model fine-tuned for diverse biomedical tasks. It aims to facilitate communication between healthcare professionals and patients, provide medical information, and assist in diagnosis, biomedical knowledge discovery, drug development, and personalized healthcare solutions. The model is based on the Qwen-7B-base model and has been fine-tuned using rich bilingual instruction data. It covers tasks such as question answering, biomedical dialogue, medical report generation, biomedical information extraction, machine translation, title generation, text classification, and text semantic similarity. The project also provides standardized data formats, model training details, model inference guidelines, and overall performance metrics across various BioNLP tasks.

Scientific Large Language Models (Sci-LLMs) is a repository that collects papers on scientific large language models, focusing on biology and chemistry domains. It includes textual, molecular, protein, and genomic languages, as well as multimodal language. The repository covers various large language models for tasks such as molecule property prediction, interaction prediction, protein sequence representation, protein sequence generation/design, DNA-protein interaction prediction, and RNA prediction. It also provides datasets and benchmarks for evaluating these models. The repository aims to facilitate research and development in the field of scientific language modeling.

Generative AI models have shown tremendous usefulness in increasing accessibility and automation of a wide range of tasks. This repository contains the `biochatter` Python package, a generic backend library for the connection of biomedical applications to conversational AI. It aims to provide a common framework for deploying, testing, and evaluating diverse models and auxiliary technologies in the biomedical domain. BioChatter is part of the BioCypher ecosystem, connecting natively to BioCypher knowledge graphs.

KG-RAG (Knowledge Graph-based Retrieval Augmented Generation) is a task agnostic framework that combines the explicit knowledge of a Knowledge Graph (KG) with the implicit knowledge of a Large Language Model (LLM). KG-RAG extracts "prompt-aware context" from a KG, which is defined as the minimal context sufficient enough to respond to the user prompt. This framework empowers a general-purpose LLM by incorporating an optimized domain-specific 'prompt-aware context' from a biomedical KG. KG-RAG is specifically designed for running prompts related to Diseases.

The LLMEvaluation repository is a comprehensive compendium of evaluation methods for Large Language Models (LLMs) and LLM-based systems. It aims to assist academics and industry professionals in creating effective evaluation suites tailored to their specific needs by reviewing industry practices for assessing LLMs and their applications. The repository covers a wide range of evaluation techniques, benchmarks, and studies related to LLMs, including areas such as embeddings, question answering, multi-turn dialogues, reasoning, multi-lingual tasks, ethical AI, biases, safe AI, code generation, summarization, software performance, agent LLM architectures, long text generation, graph understanding, and various unclassified tasks. It also includes evaluations for LLM systems in conversational systems, copilots, search and recommendation engines, task utility, and verticals like healthcare, law, science, financial, and others. The repository provides a wealth of resources for evaluating and understanding the capabilities of LLMs in different domains.

cellseg-models.pytorch is a Python library built upon PyTorch for 2D cell/nuclei instance segmentation models. It provides multi-task encoder-decoder architectures and post-processing methods for segmenting cell/nuclei instances. The library offers high-level API to define segmentation models, open-source datasets for training, flexibility to modify model components, sliding window inference, multi-GPU inference, benchmarking utilities, regularization techniques, and example notebooks for training and finetuning models with different backbones.

ceLLama is a streamlined automation pipeline for cell type annotations using large-language models (LLMs). It operates locally to ensure privacy, provides comprehensive analysis by considering negative genes, offers efficient processing speed, and generates customized reports. Ideal for quick and preliminary cell type checks.

OpenCRISPR is a set of free and open gene editing systems designed by Profluent Bio. The OpenCRISPR-1 protein maintains the prototypical architecture of a Type II Cas9 nuclease but is hundreds of mutations away from SpCas9 or any other known natural CRISPR-associated protein. You can view OpenCRISPR-1 as a drop-in replacement for many protocols that need a cas9-like protein with an NGG PAM and you can even use it with canonical SpCas9 gRNAs. OpenCRISPR-1 can be fused in a deactivated or nickase format for next generation gene editing techniques like base, prime, or epigenome editing.

PINNACLE is a flexible geometric deep learning approach that trains on contextualized protein interaction networks to generate context-aware protein representations. It provides protein representations split across various cell-type contexts from different tissues and organs. The tool can be fine-tuned to study the genomic effects of drugs and nominate promising protein targets and cell-type contexts for further investigation. PINNACLE exemplifies the paradigm of incorporating context-specific effects for studying biological systems, especially the impact of disease and therapeutics.

AICSImageIO is a Python tool for Image Reading, Metadata Conversion, and Image Writing for Microscopy Images. It supports various file formats like OME-TIFF, TIFF, ND2, DV, CZI, LIF, PNG, GIF, and Bio-Formats. Users can read and write metadata and imaging data, work with different file systems like local paths, HTTP URLs, s3fs, and gcsfs. The tool provides functionalities for full image reading, delayed image reading, mosaic image reading, metadata reading, xarray coordinate plane attachment, cloud IO support, and saving to OME-TIFF. It also offers benchmarking and developer resources.

Grand Challenge is a platform that provides access to large amounts of annotated training data, objective comparisons of state-of-the-art machine learning solutions, and clinical validation using real-world data. It assists researchers, data scientists, and clinicians in collaborating to develop robust machine learning solutions to problems in biomedical imaging.

The 'machine-learning-research' repository is a comprehensive collection of resources related to mathematics, machine learning, deep learning, artificial intelligence, data science, and various scientific fields. It includes materials such as courses, tutorials, books, podcasts, communities, online courses, papers, and dissertations. The repository covers topics ranging from fundamental math skills to advanced machine learning concepts, with a focus on applications in healthcare, genetics, computational biology, precision health, and AI in science. It serves as a valuable resource for individuals interested in learning and researching in the fields of machine learning and related disciplines.

A repository that lists papers related to Large Language Model (LLM) based agents. The repository covers various topics including survey, planning, feedback & reflection, memory mechanism, role playing, game playing, tool usage & human-agent interaction, benchmark & evaluation, environment & platform, agent framework, multi-agent system, and agent fine-tuning. It provides a comprehensive collection of research papers on LLM-based agents, exploring different aspects of AI agent architectures and applications.

The `Call-for-Reviewers` repository aims to collect the latest 'call for reviewers' links from various top CS/ML/AI conferences/journals. It provides an opportunity for individuals in the computer/ machine learning/ artificial intelligence fields to gain review experience for applying for NIW/H1B/EB1 or enhancing their CV. The repository helps users stay updated with the latest research trends and engage with the academic community.

LLM-PowerHouse is a comprehensive and curated guide designed to empower developers, researchers, and enthusiasts to harness the true capabilities of Large Language Models (LLMs) and build intelligent applications that push the boundaries of natural language understanding. This GitHub repository provides in-depth articles, codebase mastery, LLM PlayLab, and resources for cost analysis and network visualization. It covers various aspects of LLMs, including NLP, models, training, evaluation metrics, open LLMs, and more. The repository also includes a collection of code examples and tutorials to help users build and deploy LLM-based applications.

This repository contains a curated list of resources on generative information retrieval, including research papers, datasets, tools, and applications. Generative information retrieval is a subfield of information retrieval that uses generative models to generate new documents or passages of text that are relevant to a given query. This can be useful for a variety of tasks, such as question answering, summarization, and document generation. The resources in this repository are intended to help researchers and practitioners stay up-to-date on the latest advances in generative information retrieval.

KG-LLM-Papers is a repository that collects papers integrating knowledge graphs (KGs) and large language models (LLMs). It serves as a comprehensive resource for research on the role of KGs in the era of LLMs, covering surveys, methods, and resources related to this integration.

Efficient Multimodal Large Language Models: A Survey provides a comprehensive review of efficient and lightweight Multimodal Large Language Models (MLLMs), focusing on model size reduction and cost efficiency for edge computing scenarios. The survey covers the timeline of efficient MLLMs, research on efficient structures and strategies, and applications. It discusses current limitations and future directions in efficient MLLM research.

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